Skip to content
Cisco ISE Vulnerability Exploited as 0day by APT (Campaign)

Cisco ISE Vulnerability Exploited as 0day by APT (Campaign)

Wiz [email protected] (Wiz Threat Research) November 13, 2025

Researchers uncovered an advanced persistent threat (APT) exploiting zero-day vulnerabilities in Cisco Identity Services Engine (ISE) and Citrix systems (CitrixBleed2). The vulnerabilities, tracked as CVE-2025-20337 and CVE-2025-5777, were leveraged by the attackers to deploy custom malware. While CVE-2025-5777 has been previously covered, the zero-day exploitation of CVE-2025-20337 represents a new development.

Amazon’s honeypots first detected exploitation of a previously unknown Citrix vulnerability (now CVE-2025-5777, “Citrix Bleed Two”) before public disclosure, indicating active zero-day exploitation. During related activity, Amazon identified a separate exploit targeting Cisco ISE through an undocumented endpoint. This vulnerability, later designated CVE-2025-20337, involved insecure deserialization logic that allowed pre-authentication remote code execution and full administrative compromise.

Post-exploitation, attackers deployed a custom in-memory web shell disguised as a legitimate Cisco ISE component named IdentityAuditAction. The shell utilized Java reflection and Tomcat listeners to intercept HTTP requests, encrypting communications using DES with non-standard Base64 encoding. No IOCs have been published for this activity.

Extracted Entities

Attack Types (2)

Companies (2)

Platforms (3)

Vulnerabilities (1)